ON the Surgical Service of the Veterans Administration Hospital, Providence, Rhode Island, we have had the opportunity to observe and treat 3 brothers with an unusual combination of abnormalities.In reviewing the literature we have found a similar syndrome described in only 1 other family. It was believed that the case histories of these brothers should be studied and reported in view of the rarity of this disease syndrome.Gardner et al.123 reported multiple cutaneous and subcutaneous lesions occurring simultaneously with multiple polyposis of the colon and osteomas in 6 members of a family group of 51 living persons. Forty-four . . .