Interferon action—sequence specificity of the ppp(A2′p)nA-dependent ribonuclease
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 289 (5796), 414-417
- https://doi.org/10.1038/289414a0
Abstract
The sequence specificities of the 2-5A-dependent RNases in extracts of rabbit reticulocytes, mouse ascites tumor cells and human lymphoblastoid cells were investigated in conditions of partial digestion using terminally labeled RNA substrates [La crosse virus and influenza virus genomes]. The enzymes cleaved on the 3''-side of UN sequences to yield UpNp terminated products. Cleavage was observed predominantly at UA and UU sequences.This publication has 23 references indexed in Scilit:
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