HISTOCHEMICAL DEMONSTRATION OF KETOSTEROIDS IN ADRENAL CORTICAL TUMORS WITH OR WITHOUT AN ASSOCIATED CUSHING’S SYNDROME1
- 29 February 1952
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 50 (3), 338-349
- https://doi.org/10.1210/endo-50-3-338
Abstract
Adrenal cortical tumors associated with Cushing''s syndrome contained active lipoidal ketonic carbonyl groups (presumably corticosteroids) when fixed in formalin for brief periods (mos.) and little or no carbonyl groups (presumably other ketosteroids) when fixed in formalin for yrs. The solubility of the corticosteroids in water though slight is believed to explain this phenomenon. Six of 9 adrenal cortical tumors not known to be associated with Cushing''s tumor or virilism contained active ketonic carbonyl groups in the lipoid droplets of the tumor cells (presumably 1 or more of the ketosteroids).Keywords
This publication has 4 references indexed in Scilit:
- HISTOCHEMICAL DEMONSTRATION OF KETOSTEROIDS IN NORMAL AND NEOPLASTIC TESTES1Endocrinology, 1951
- HISTOCHEMICAL DEMONSTRATION OF KETOSTEROIDS IN VIRILIZING TUMORS OF THE ADRENAL CORTEX1Endocrinology, 1951
- Histochemical demonstration of latent active carbonyl groups in normal and neoplastic nervous tissueCancer, 1951
- THE EXTRACTION OF CORTIN-LIKE SUBSTANCES FROM HUMAN POST-OPERATIVE URINE1Endocrinology, 1944