Effect of formulation on the bioavailability of retinol, d-α-tocopherol and riboflavine
- 1 July 1984
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 36 (7), 461-464
- https://doi.org/10.1111/j.2042-7158.1984.tb04426.x
Abstract
Formulation factors influencing vitamin bioavailability have been investigated, with vitamins A, E and B2, formulated in a new liquid vehicle (Aqua-Biosorb) and encapsulated into soft gelatin capsules, being compared with commercial formulations. There was an enhanced vitamin bioavailability from the new vehicle which appeared to be related to the surfactant system employed and the absence of vegetable oil in the formulation.Keywords
This publication has 4 references indexed in Scilit:
- Plasma and tissue levels of dietary radiotocopherols in the harp seal, Phoca groenlandicaCanadian Journal of Physiology and Pharmacology, 1977
- Effect of the hydrophile-lipophile balance of non-ionic detergents (Triton X-series) on the solubilization of biological membranes and their integral b-type cytochromesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- Biological implications of the use of surfactants in medicines: and the biphasic effects of surfactants in biological systemsPesticide Science, 1975
- Comparative absorption, excretion, and storage of oily and aqueous preparations of vitamin AThe Journal of Pediatrics, 1947