Evidence of Henipavirus Infection in West African Fruit Bats
Open Access
- 23 July 2008
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 3 (7), e2739
- https://doi.org/10.1371/journal.pone.0002739
Abstract
Henipaviruses are emerging RNA viruses of fruit bat origin that can cause fatal encephalitis in man. Ghanaian fruit bats (megachiroptera) were tested for antibodies to henipaviruses. Using a Luminex multiplexed microsphere assay, antibodies were detected in sera of Eidolon helvum to both Nipah (39%, 95% confidence interval: 27–51%) and Hendra (22%, 95% CI: 11–33%) viruses. Virus neutralization tests further confirmed seropositivity for 30% (7/23) of Luminex positive serum samples. Our results indicate that henipavirus is present within West Africa.Keywords
This publication has 15 references indexed in Scilit:
- Person-to-Person Transmission of Nipah Virus in a Bangladeshi CommunityEmerging Infectious Diseases, 2007
- Neutralization assays for differential henipavirus serology using Bio-Plex Protein Array SystemsJournal of Virological Methods, 2007
- Henipavirus and Tioman Virus Antibodies in Pteropodid Bats, MadagascarEmerging Infectious Diseases, 2007
- Receptor Binding, Fusion Inhibition, and Induction of Cross-Reactive Neutralizing Antibodies by a Soluble G Glycoprotein ofHendra VirusJournal of Virology, 2005
- Nipah Virus Infection in Bats (Order Chiroptera) in Peninsular MalaysiaEmerging Infectious Diseases, 2001
- Nipah Virus: A Recently Emergent Deadly ParamyxovirusScience, 2000
- Fatal encephalitis due to Nipah virus among pig-farmers in MalaysiaThe Lancet, 1999
- A Morbillivirus that Caused Fatal Fisease in Horses and HumansScience, 1995
- Eidolon helvumMammalian Species, 1988
- The Bats of West AfricaJournal of Mammalogy, 1968