Effect of histamine H1-and H2-receptor blockade on canine gastric acid secretion
- 1 March 1978
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 23 (3), 222-224
- https://doi.org/10.1007/bf01072321
Abstract
In dogs with gastric fistulae and Heidenhain pouches, inhibition of histamine-stimulated gastric acid secretion by the histamine H2-receptor antagonist metiamide is not increased by the addition of a histamine H1-receptor antagonist (mepyramine maleate). Under the conditions of this study there is no evidence for the presence of histamine H1-receptor sites on the gastric parietal cell.This publication has 10 references indexed in Scilit:
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