Intestinal Absorption of Glucose in Hypothalamic Obesity
- 1 November 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (2), 410-412
- https://doi.org/10.3181/00379727-81-19893
Abstract
Electrocoagulation of certain hypothalamic areas in rats resulted in hypothalamic obesity (HO). Intestinal absorption rates for glucose were detd. GCA (glucose coeff. of absorption = mg. glucose absorbed/l00g./hr.) values were: control-114.0, HO-107.4; HO thyroxine-treated-173.5, control thyroxine-treated-191.6, thyroidectomized-75.2. Marked obesity occurred in some cases without excessive wt. gain. Apparently hypothalamic lesions resulting in obesity neither elevate intestinal absorption rate for glucose nor impair the thyroxine-induced increase of this function. They may impair the secretion of growth hormone.Keywords
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