Feeding Produced in the Satiated Rat by Elevating the Concentration of Calcium in the Brain
- 9 June 1972
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 176 (4039), 1124-1125
- https://doi.org/10.1126/science.176.4039.1124
Abstract
When the concentration of calcium ions in the cerebral ventricles is elevated, a fully satiated rat eats voraciously. This feeding response is not prevented by prior intraventricular administration of alpha-or beta-adrenergic blocking agents, or other pharmacological antagonists. This supports the concept of an independent ionic mechanism, rather than a neurotransmitter one, for modulating a "set-point" for weight or hunger.Keywords
This publication has 24 references indexed in Scilit:
- Temperature changes in the rat produced by altering the sodium-calcium ratio in the cerebral ventriclesNeuropharmacology, 1972
- Emotional behavior, arousal and sleep produced by sodium and calcium ions perfused within the hypothalamus of the catPhysiology & Behavior, 1971
- Spontaneous feeding in the satiated cat evoked by sodium or calcium ions perfused within the hypothalamusPhysiology & Behavior, 1971
- Norepinephrine: Reversal of Anorexia in Rats with Lateral Hypothalamic DamageScience, 1971
- Distribution of Pethidine and Chlorpromazine in Maternal, Foetal and Neonatal Biological FluidsNature, 1971
- Body Temperature: Possible Ionic Mechanism in the Hypothalamus Controlling the Set PointScience, 1970
- Relationship of body weight to the lateral hypothalamic feeding syndrome.Journal of Comparative and Physiological Psychology, 1970
- Chemical activation of ingestive and other hypothalamic regulatory mechanismsPhysiology & Behavior, 1968
- Feeding and temperature responses in the unrestrained rat after injections of cholinergic and aminergic substances into the cerebral ventriclesPhysiology & Behavior, 1968
- A simplified intracranial cannula for chemical stimulation or long-term infusion of the brainPhysiology & Behavior, 1967