Studies on the Synthesis of Tedanolide: Synthesis of the C(5)−C(21) Segment via a Highly Stereoselective Fragment Assembly Aldol Reaction of a Chiral β,γ-Unsaturated Methyl Ketone
- 24 May 1999
- journal article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 1 (1), 95-98
- https://doi.org/10.1021/ol990572s
Abstract
A highly diastereoselective synthesis of 3, corresponding to the C(5)−C(21) segment of tedanolide, has been accomplished by a route utilizing the aldol reaction of aldehyde 4 and the β,γ-unsaturated methyl ketone 5.Keywords
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