Central nervous system involvement in sle
- 1 April 1977
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 20 (3), 869-878
- https://doi.org/10.1002/art.1780200317
Abstract
The clinical course and diagnostic profile of 13 patients with central nervous system involvement and systemic lupus erythematosus (CNS‐SLE) are presented. The diagnostic yield for each procedure was measured as the percent abnormal: CSF total protein was 38%; increased CSF IgG 69%; decreased CSF hemolytic C4 10%; increased CSF anti‐DNA 64%; electroencephalogram 80%; flow brain scan 50%; and static brain scan 0%. No single procedure was consistently abnormal, but the battery of tests provided a useful and specific CNS‐SLE diagnostic profile.Keywords
This publication has 21 references indexed in Scilit:
- Deoxyribonucleic acid strandedness. Partial characterization of the antigenic regions binding antibodies in lupus erythematosus serum.JCI Insight, 1975
- Renal histology and clinical course of systemic lupus erythematosusArthritis & Rheumatism, 1973
- The Fourth Component of Complement in the Cerebrospinal Fluid in Systemic Lupus ErythematosusArthritis & Rheumatism, 1973
- Host Immunoglobulin G and Complement Deposits in the Choroid Plexus during Spontaneous Immune Complex DiseaseScience, 1973
- DNA:Anti-DNA Complexes: Their Detection in Systemic Lupus Erythematosus SeraJCI Insight, 1973
- IgG levels in cerebrospinal fluid of patients with central nervous system manifestations of systemic lupus erythematosusClinical Immunology and Immunopathology, 1972
- SERUM AND CEREBRAL SPINAL FLUID COMPLEMENT AND SERUM AUTOANTIBODIES IN SYSTEMIC LUPUS ERYTHEMATOSUSMedicine, 1971
- Iodination of nucleic acids in vitroBiochemistry, 1971
- THE NATURAL HISTORY OF SYSTEMIC LUPUS ERYTHEMATOSUS BY PROSPECTIVE ANALYSISMedicine, 1971
- THE NEUROLOGICAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUSMedicine, 1968