The role of glycophosphatidylinositol anchor in the amplification of the scrapie isoform of prion protein in vitro

Abstract
Transmissible spongiform encephalopathies are associated with an autocatalytic conversion of normal prion protein, PrPC, to a protease-resistant form, PrPres. This autocatalytic reaction can be repro...
Funding Information
  • National Institutes of Health (NS44158, AG14359)