EXPERIMENTAL CALCIUM-OXALATE NEPHROLITHIASIS IN THE RAT - ROLE OF THE RENAL PAPILLA
- 1 January 1982
- journal article
- research article
- Vol. 107 (1), 59-69
Abstract
Calcium oxalate nephrolithiasis in rats, induced by a single i.p. injection of sodium oxalate, is associated with pathologic changes in the renal papillary tip. Calcium oxalate crystals appear in the tubular lumens, in the intercellular spaces between epithelial cells, and attached to the tubular epithelial basal lamina. Unusual paracrystalline structures also develop in the distal tubule associated with the basal lamina. Speculations are made about the role of these structures. The epithelial changes are primarily necrotic and are similar to those described in experimental papillary necrosis. Complete morphologic recovery occurs in 1-2 wk.This publication has 28 references indexed in Scilit:
- THE MICROGENESIS OF SOME RENAL CALCULI1981
- Calcium oxalate crystal-induced cytolysis in polymorphonuclear leukocytes and erythrocytesInflammation Research, 1980
- Crystal deposition in the renal tubules of hyperoxaluric and hypomagnesemic rats.1980
- Ultrastructural events in early calcium oxalate crystal formation in ratsKidney International, 1979
- Primary renal calculi: Anderson-Carr-Randall progression?American Journal of Roentgenology, 1979
- HISTOLOGIC FIXATIVES SUITABLE FOR DIAGNOSTIC LIGHT AND ELECTRON-MICROSCOPY1976
- ULTRASTRUCTURE OF FUNCTIONING KIDNEY1967
- EARLY MORPHOLOGIC CHANGES IN SERUM-INDUCED RENAL PAPILLARY NECROSIS - LIGHT AND ELECTRON MICROSCOPIC STUDIES1967
- PRODUCTION OF CALCIUM OXALATE RENAL CALCULI IN VITAMIN-B-6-DEFICIENT RATS - STUDY OF THE INFLUENCE OF URINE PH1960
- A NEW THEORY ON THE FORMATION OF RENAL ALCULI1British Journal of Urology, 1954