Evidence for the existence of HLA A11 subgroups in Hong Kong Chinese

Abstract

A study of 771 consecutive blood samples from Hong Kong Chinese has shown the existence of two variants of HLA A11 which can be recognized by antisera of Chinese and other origins. The two variants, identified as HLA A11S (for Short) and HLA A11L (for Long) occurred in 6.4% and 45.9%, respectively, of the samples tested, 2.6% of the samples gave reactions consistent with the presence of both variants and in one case this could be verified by a family study. Segregation of the variants was evident in two other families.