The H+/O ratio of proton translocation linked to the oxidation of succinate by mitochondria
- 10 December 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 178 (2), 187-192
- https://doi.org/10.1016/0014-5793(84)80598-0
Abstract
In a recent communication Lehninger and co-workers (Costa L.E., Reynaferje B., and Lehninger A.L. (1984) J. Biol. Chem. 259, 4802-4811) reported values approaching 8 for the H+/O ratio of vectorial proton ejection from rat liver mitochondria respiring with succinate. Here we present a rigorous analysis of these measurements which reveals that they may significantly overestimate the true H+/O stoicheiometry.Keywords
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