Dual Functions of Streptococcus salivarius Urease
- 15 August 2000
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 182 (16), 4667-4669
- https://doi.org/10.1128/jb.182.16.4667-4669.2000
Abstract
A urease-deficient derivative of Streptococcus salivarius 57.I was constructed by allelic exchange at the ureC locus. The wild-type strain was protected against acid killing through hydrolysis of physiologically relevant concentrations of urea, whereas the mutant was not. Also, S. salivarius could use urea as a source of nitrogen for growth exclusively through a urease-dependent pathway.Keywords
This publication has 14 references indexed in Scilit:
- A H + -Gated Urea Channel: The Link Between Helicobacter pylori Urease and Gastric ColonizationScience, 2000
- Oral Streptococci... Products of Their EnvironmentJournal of Dental Research, 1998
- Analysis ofStreptococcus salivariusurease expression using continuous chemostat cultureFEMS Microbiology Letters, 1996
- Helicobacter pylori nickel‐transport gene nixA: synthesis of catalytically active urease in Escherichia coli independent of growth conditionsMolecular Microbiology, 1995
- Bacterial ureases: structure, regulation of expression and role in pathogenesisMolecular Microbiology, 1993
- Urease activity in Streptococcus salivarius at low pHArchives of Oral Biology, 1993
- pH Regulation by Streptococcus mutansJournal of Dental Research, 1992
- The Origin and Fate of Salivary Urea and Ammonia in ManClinical Science, 1977
- Detection of specific sequences among DNA fragments separated by gel electrophoresisJournal of Molecular Biology, 1975
- Urea content of gingival crevicular fluid and its relation to periodonal disease in humansJournal of Periodontal Research, 1971