Influence of a Fat-Enriched Meal on Human Serum (L-Phenylalanine-Sensitive) "Intestinal" Alkaline Phosphatase.

Abstract

In 2 out of 4 subjects ingesting break-fast containing 27. 3 g of fat, a transient increase of the L-phenylalanine-sensitive "intestinal" alkaline phosphatase isoenzyme occurred in the serum. In 4 out of 4 subjects ingesting breakfast with higher fat content (69. 6 g) the rise appeared and persisted for 4 hr. In-dividuals differed greatly in the pattern of serum enzyme partition which were exhibited. Fat absorption is linked with the later appearance in the serum of the L-phenylalanine-sensitive isoenzyme of alkaline phosphatase.