Damage to Hypothalamic Dopaminergic Neurons Is Associated with Development of Prolactin-Secreting Pituitary Tumors
- 12 November 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 218 (4573), 684-686
- https://doi.org/10.1126/science.7134966
Abstract
Old female rats with spontaneous prolactin-secreting pituitary tumors (prolactinomas) and young females with prolactinomas produced by prolonged estrogen treatment had damaged tuberoinfundibular dopaminergic neurons. Since these neurons inhibit the function of pituitary prolactin-secreting cells, their destruction may lead to development of prolactinomas.This publication has 21 references indexed in Scilit:
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