EFFECTS OF RESERPINE ON BLOOD‐PRESSURE RESPONSES EVOKED FROM THE HYPOTHALAMUS
Open Access
- 1 March 1957
- journal article
- Published by Wiley in British Journal of Pharmacology and Chemotherapy
- Vol. 12 (1), 8-11
- https://doi.org/10.1111/j.1476-5381.1957.tb01353.x
Abstract
Different areas of the hypothalamus were stimulated by a stereotaxic technique before and after reserpine in unanaesthetized cats. Reserpine in a dose of 1 mg./kg. body weight increased the threshold of stimulation of hypothalamic areas in cats giving an initial pressor response. It decreased the threshold of stimulation of areas of the hypothalamus in animals giving an initial depressor response. Reserpine thus appeared to affect the hypothalamus directly in two ways. It depressed the sympathetic centres in the diencephalon and facilitated the parasympathetic ones.Keywords
This publication has 9 references indexed in Scilit:
- Further Characterization of Central Effects of Reserpine (Serpasil)American Journal of Physiology-Legacy Content, 1955
- Drug therapy in hypertension; a critical review.1955
- EFFECTS OF RAUWOLFIA ALKALOIDS ON HYPOTHALAMIC, MEDULLARY AND SPINAL VASOREGULATORY SYSTEMS1955
- RAUWOLFIA SERPENTINA IN THE TREATMENT OF HIGH BLOOD-PRESSUREThe Lancet, 1954
- [The effect of serpasil (reserpin, a new alkaloid from Rauwolfia serpentina B.) on isolated circulatory organs].1954
- CARDIOVASCULAR AND RESPIRATORY EFFECTS OF SERPASIL, A NEW CRYSTALLINE ALKALOID FROM RAUWOLFIA SERPENTINA BENTH, IN THE DOG1954
- Zur Pharmakologie des Reserpin, eines neuen Alkaloids ausRauwolfia Serpentina BenthCellular and Molecular Life Sciences, 1953
- The action of rauwolfia serpentina on vasomotor reflexesNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1953
- Increase of Food Intake Induced by Electrical Stimulation of the Lateral HypothalamusAmerican Journal of Physiology-Legacy Content, 1952