A Comparative Study of a Monoclonal Immunoassay Reagent Strip Test and High Pressure Liquid Chromatography for Theophylline
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology: Clinical Toxicology
- Vol. 25 (3), 231-241
- https://doi.org/10.3109/15563658708992627
Abstract
Our experience with the determination of theophylline in serum using a monoclonal immunoassay reagent strip test is reported. The day-to-day precision of a series of drug assay controls (n = 74) was investigated with a mean theophylline value of 15.3 .+-. 1.2 mg/l. Interference and/or cross reactivity of structurally related compounds and metabolites of theophylline was tested. Serum samples from 148 asthmatic patients who were treated with theophylline were analyzed by SERALYZER ARIS reagent strip test and by high pressure liquid chromatography. A correlation coefficient of 0.99 was found between these techniques using a linear regression analysis.This publication has 8 references indexed in Scilit:
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