THE EFFECT OF PROLONGED TESTOSTERONE PROPIONATE ADMINISTRATION ON THE IMMATURE AND ADULT FEMALE RAT
- 1 February 1939
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 24 (2), 175-181
- https://doi.org/10.1210/endo-24-2-175
Abstract
In immature rats, prolonged adm. of the hormone caused decreased wt. of pituitary, adrenals, ovary, uterine horns, and inhibition of estrus with mucification of vaginal epithelium. The degree of uterine atrophy was not in proportion to the ovarian atrophy. The adult rat reacted similarly, except that the pituitary showed no significant wt. decrease. The deleterious effect of prolonged testosterone treatment on the ovaries was temporary. Restitution of structure and function occurred within 29 days.This publication has 1 reference indexed in Scilit:
- The bisexual and co‐operative properties of the sex hormones as shown by the histological investigation of the sex organs of female rats treated with these hormonesThe Journal of Pathology and Bacteriology, 1937