Effect of Dilution Rate and Mg2+ Limitation on Toxic Shock Syndrome Toxin-1 Production by Staphylococcus aureus Grown in Defined Continuous Culture
- 1 March 1988
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 134 (3), 719-723
- https://doi.org/10.1099/00221287-134-3-719
Abstract
SUMMARY: A toxic shock syndrome isolate of Staphylococcus aureus was grown in a chemostat, in a defined synthetic medium of six amino acids, glucose, two vitamins and salts. Steady states were achieved under limiting and replete Mg2+ conditions and at a range of relative specific growth rates. The biomass and toxic shock syndrome toxin-1 (TSST-1) were estimated at each condition. Under Mg2- limitation the biomass and TSST-1 production rates were reduced compared to Mg2+ replete conditions. Optimal TSST-1 production occurred at 0.81 relative specific growth rate.This publication has 13 references indexed in Scilit:
- Purification and characterization of Staphylococcus aureus FRI 1169 and 587 toxic shock syndrome exotoxinsInfection and Immunity, 1984
- TOXIC SHOCK SYNDROME STAPHYLOCOCCUS-AUREUS - EFFECT OF TAMPONS ON TOXIC SHOCK SYNDROME TOXIN-1 PRODUCTION1984
- Tampon-induced changes in vaginal oxygen and carbon dioxide tensionsAmerican Journal of Obstetrics and Gynecology, 1984
- Production of Staphylococcal Pyrogenic Exotoxin Type C: Influence of Physical and Chemical FactorsThe Journal of Infectious Diseases, 1983
- Effects of Glucose Concentration on Biomass, Maximum Specific Growth Rate and Extracellular Enzyme Production by Three Species of Cutaneous Propionibacteria Grown in Continuous CultureMicrobiology, 1981
- Identification and Characterization of an Exotoxin from Staphylococcus aureus Associated with Toxic-Shock SyndromeThe Journal of Infectious Diseases, 1981
- Toxic-Shock Syndrome in Menstruating WomenNew England Journal of Medicine, 1980
- Toxic-Shock SyndromeNew England Journal of Medicine, 1980
- TOXIC-SHOCK SYNDROME ASSOCIATED WITH PHAGE-GROUP-I STAPHYLOCOCCIThe Lancet, 1978
- Dependency on Medium and Temperature of Cell Size and Chemical Composition during Balanced Growth of Salmonella typhimuriumJournal of General Microbiology, 1958