Inhibition of Histone Deacetylase 6 Acetylates and Disrupts the Chaperone Function of Heat Shock Protein 90
Top Cited Papers
Open Access
- 1 July 2005
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 280 (29), 26729-26734
- https://doi.org/10.1074/jbc.c500186200
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Histone deacetylase 3 (HDAC3) activity is regulated by interaction with protein serine/threonine phosphatase 4Genes & Development, 2005
- Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3Blood, 2005
- Synergistic Induction of Oxidative Injury and Apoptosis in Human Multiple Myeloma Cells by the Proteasome Inhibitor Bortezomib and Histone Deacetylase InhibitorsClinical Cancer Research, 2004
- Cotreatment with 17-Allylamino-Demethoxygeldanamycin and FLT-3 Kinase Inhibitor PKC412 Is Highly Effective against Human Acute Myelogenous Leukemia Cells with Mutant FLT-3Cancer Research, 2004
- The NucleosomeCell, 2004
- Dissection of the Contribution of Individual Domains to the ATPase Mechanism of Hsp90Journal of Biological Chemistry, 2003
- Histone deacetylase inhibitors in cancer therapyCancer Cell, 2003
- Controlling the double helixNature, 2003
- Molecular Chaperones in the Cytosol: from Nascent Chain to Folded ProteinScience, 2002
- Histone deacetylases and cancer: causes and therapiesNature Reviews Cancer, 2001