A note on the absorption of 3-methoxy-N-methyl-morphinan hydrochloride from the rat stomach
- 1 February 1968
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 20 (2), 98-101
- https://doi.org/10.1111/j.2042-7158.1968.tb09696.x
Abstract
(+)-3-Methoxy-N-methylmorphinan, a base with a pKa of 7·97 is absorbed from the rat stomach at pH 2·0, in a manner which suggests passive diffusion rather than a specialized transport process to be the mechanism.This publication has 5 references indexed in Scilit:
- Ion pair extraction of pharmaceutical amines. Role of dipolar solvating agents in extraction of dextromethorphanAnalytical Chemistry, 1967
- An in vitro model for soluble drug absorptionJournal of Pharmacy and Pharmacology, 1967
- Physical Chemical Study of the Distribution of Some Amine Salts Between Immiscible Solvents. IIJournal of Pharmaceutical Sciences, 1964
- Physical Chemical Study of the Distribution of Some Amine Salts Between Immiscible SolventsJournal of Pharmaceutical Sciences, 1961
- Phospholipids. 3. On the chromatographic separation of glycerophospholipidsBiochemical Journal, 1955