The vitamin B2 complex of liver: The identity of the liver filtrate factor with pantothenic acid

Abstract

Liver filtrate factor is identical with pantothenic acid. Evidence is presented that the factor in liver extracts which is neither adsorbed by Fuller''s earth nor extracted from acid aqueous soln. by amyl alc. is a biological entity (factor [beta]) and that a 3d unidentified factor ([gamma]) is present in acid-autoclaved whole extract of liver. A synthesis of [gamma]:[delta]-dihydroxyvaleryl-[beta]-alanine methyl ester is descr.