Induction by Phorbol Esters of Macrophage Differentiation in Human Leukaemia Cell Lines does not Require Cell Division
- 12 March 1981
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 47 (3), 479-483
- https://doi.org/10.1111/j.1365-2141.1981.tb02816.x
Abstract
Phorbol esters can induce differentiation into macrophage-like cells in the 2 human myeloid leukemia cell lines HL-60 and KG-1. Phorbol ester-induced differentiation of blast cells into cells with the morphologic, histochemical and phagocytic characteristics of macrophages did not require 3H-thymidine incorporation. Phorbol ester induced macrophage differentiation does not require DNA synthesis.This publication has 19 references indexed in Scilit:
- Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesisNature, 1980
- Induction of Differentiation in Human Promyelocytic Leukemia Cells by Tumor PromotersScience, 1979
- The requirement of DNA synthesis for the induction of alkaline phosphatase by bromodeoxyuridine in a derivative of the HeLa cell lineJournal of Cellular Physiology, 1979
- Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesisCell, 1978
- Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemiaNature, 1978
- Acute Myelogenous Leukemia: A Human Cell Line Responsive to Colony-Stimulating ActivityScience, 1978
- Continuous growth and differentiation of human myeloid leukaemic cells in suspension cultureNature, 1977
- The dependence of erythroid differentiation on cell replication in dimethyl sulfoxide-treated friend leukemia-virus-infected cellsBiochemical and Biophysical Research Communications, 1976
- Differentiation of Erythroleukemic Cells in the Presence of Inhibitors of DNA SynthesisScience, 1975
- The requirement for DNA synthesis and gene expression in the generation of cytotoxicity in vitro.The Journal of Experimental Medicine, 1975