PKCθ is required for hemostasis and positive regulation of thrombin-induced platelet aggregation and α-granule secretion
- 1 July 2009
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 385 (1), 22-27
- https://doi.org/10.1016/j.bbrc.2009.05.021
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- ThrombinMolecular Aspects of Medicine, 2008
- Impaired hemostasis and protection against thrombosis in protease‐activated receptor 4‐deficient mice is due to lack of thrombin signaling in plateletsJournal of Thrombosis and Haemostasis, 2004
- Protein Kinase Cθ in T Cell ActivationAnnual Review of Immunology, 2002
- Role of thrombin signalling in platelets in haemostasis and thrombosisNature, 2001
- PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytesNature, 2000
- Regulation of Protein Kinase Cθ Function during T Cell Activation by Lck-mediated Tyrosine PhosphorylationJournal of Biological Chemistry, 2000
- Protein Kinase C-θ (PKCθ) Distribution Analysis in Hematopoietic Cells: Proliferating T Cells Exhibit High Proportions of PKCθ in the Particulate FractionCellular Immunology, 1999
- Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombinJournal of Clinical Investigation, 1999
- Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase CScience, 1992
- A platelet alpha granule membrane protein that is associated with the plasma membrane after activation. Characterization and subcellular localization of platelet activation-dependent granule-external membrane protein.Journal of Clinical Investigation, 1986