Familial angiolipomatosis

Abstract

Large subcutaneous angiolipomata were observed bilaterally around the wrists, knees and ankles in an adolescent boy. Growth had been slow since first noted at 1 yr of age. The tumors extended deeply between muscles, tendons and joint capsules, but without infiltration of these structures. The tumors recurred after subtotal excision. Muscular hypotrophy and deformation of bones near the affected joints were noted. An 8 yr old sister had similar tumors, suggesting a genetic etiology.