Serologic Responses to Treatment of 128 Patients with Late Latent Syphilis

Abstract

Patients (128) treated for late latent syphilis were followed. Benzathine penicillin G (2.4 .times. 106 units given i.m. once a week for 2 wk) was administered to 123 patients and 5 patients were given tetracycline (500 mg orally 4 times daily for 12 days). Of these patients, 56 (44%) became seronegative within 5 yr and 72 (56%) had persistently positive reagin tests.