Quantitation of Carbon Dioxide by High Performance Liquid Chromatography: The Key to Solubility Measurements in Liquefied Gas Solutions

Abstract

A technique is described whereby solubility data may be obtained for systems employing liquefied carbon dioxide as the solvent. Analysis of the solution is effected by the direct injection of an aliquot of pressurized liquid into a modern liquid chromatograph fitted with a reversed-phase C₁₈ column. Detection of the carbon dioxide is accomplished by a differential refractometer. After the appropriate calibrations are performed, data are obtained which compare favourably with the literature value of the solubility of naphthalene in liquid carbon dioxide.