Activation of the Cerebellum by Sensory Finger Stimulation and by Finger Opposition Movements; A Functional Magnetic Resonance Imaging Study
- 1 July 1998
- journal article
- research article
- Published by Wiley in Journal of Neuroimaging
- Vol. 8 (3), 127-131
- https://doi.org/10.1111/jon199883127
Abstract
Activation of the ipsilateral anterior lobe of the cerebellum by means of hand movements by humans is a well‐known phenomenon, but the cerebellar encoding of sensory information has not been well established. The authors delineated the representation of sensory stimulation of fingers in the anterior lobe of the cerebellum using functional magnetic resonance imaging sensitized to changes in blood oxygenation and compared these areas to the regions activated by means of finger opposition movements. Activation was determined by means of pixel‐bypixel correlation of the signal intensity time course with a reference waveform equivalent to the stimulus protocol. All subjects showed significant activation of the anterior lobe of the cerebellum, mainly located in the ipsilateral Larsell lobules IV‐V and less consistent in the vermis in relation to sensory finger stimulation. Among some subjects the authors also found activation in the anterior lobe on the contralateral side. The finger movements activated regions that overlapped with the areas activated by sensory finger stimulation but showing a larger and more intense activation pattern.Keywords
This publication has 26 references indexed in Scilit:
- Attentional Activation of the Cerebellum Independent of Motor InvolvementScience, 1997
- The Relevance of Sensory Input for the Cerebellar Control of MovementsNeuroImage, 1997
- Somatotopic motor representation in the human anterior cerebellumBrain, 1996
- Regional cerebral blood flow during a self-paced sequential finger opposition task in patients with cerebellar degenerationBrain, 1995
- Spatial patterns of functional activation of the cerebellum investigated using high field (4 T) MRINMR in Biomedicine, 1994
- Motor learning in manNeuroReport, 1990
- Somatotopic alignment between climbing fiber input and nuclear output of the cat intermediate cerebellumJournal of Comparative Neurology, 1987
- Fractured cutaneous projections to the granule cell layer of the posterior cerebellar hemisphere of the domestic catJournal of Comparative Neurology, 1984
- Organization of climbing fiber input from mechanoreceptors to lobule V vermal cortex of the catExperimental Brain Research, 1982
- Fractured Somatotopy in Granule Cell Tactile Areas of Rat Cerebellar Hemispheres Revealed by Micromapping; pp. 94–105Brain, Behavior and Evolution, 1978