Obesity
- 7 August 1997
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 337 (6), 396-407
- https://doi.org/10.1056/nejm199708073370606
Abstract
Obesity is the most common and costly nutritional problem in the United States, affecting approximately 33 percent of adults.1 Health care costs directly attributable to obesity amount to approximately $68 billion per year, and an additional $30 billion per year is spent on weight-reduction programs and special foods.2 Nevertheless, treatment directed toward the long-term reduction of body weight is largely ineffective, and 90 to 95 percent of persons who lose weight subsequently regain it.3,4 The level of energy storage, or fatness, at which the risk of morbidity increases is determined on an actuarial basis. The body-mass index (the weight . . .This publication has 107 references indexed in Scilit:
- Suggestive Linkages Between Markers on Human 1p32‐p22 and Body Fat and Insulin Levels in the Québec Family StudyObesity Research, 1997
- Mutation Screening and Identification of a Sequence Variation in the Human OB Gene Coding RegionBiochemical and Biophysical Research Communications, 1996
- Abnormal splicing of the leptin receptor in diabetic miceNature, 1996
- Brain Peptides and Obesity: Pharmacologic TreatmentObesity Research, 1995
- Nutrient Intake is Modulated By Peripheral Peptide AdministrationObesity Research, 1995
- Dexamethasone Regulates Obese Expression in Isolated Rat AdipocytesBiochemical and Biophysical Research Communications, 1995
- Evidence for linkage between a region on chromosome 1p and the acute insulin response in Pima IndiansDiabetes, 1995
- Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight GainNew England Journal of Medicine, 1988
- Energy Expenditure and Intake in Infants Born to Lean and Overweight MothersNew England Journal of Medicine, 1988
- An Adoption Study of Human ObesityNew England Journal of Medicine, 1986