Ambient hydrogen sulfide, total reduced sulfur, and hospital visits for respiratory diseases in northeast Nebraska, 1998–2000

Abstract

This analysis examined associations between total reduced sulfur (TRS) and hydrogen sulfide (H₂S) levels, and hospital visits for respiratory disease among residents of Dakota City and South Sioux City, Nebraska, from January 1998 to May 2000. For reference, the association between TRS, H₂S, and digestive diseases was also examined. Time-series analyses of daily hospital visits in the selected outcome categories and measures of TRS and H₂S were performed using generalized additive models with a Poisson link. TRS and H₂S levels were categorized as high if at least one of the daily 30-min rolling averages was ≥30 ppb and as low if every rolling average was versus a day with a low exposure. For children less than 18 years of age, a positive association was found between asthma hospital visits and 1-day lagged TRS levels. For adults, a positive association was found between asthma hospital visits and H₂S levels on the previous day. A positive association also was found between hospital visits for all respiratory diseases, and H₂S and TRS levels on the previous day for children but not for adults. No association was found between contaminant levels and hospital visits for all digestive diseases. These findings suggest that TRS or H₂S levels may be associated with exacerbations of asthma or other respiratory diseases among the residents of Dakota City and South Sioux City.