Influence of Estrogens on Total Serum Copper and Caeruloplasmin.

Abstract
Administration of estrogen as Estinyl (ethinyl estradiol) in doses ranging from 0.25 - 1.0 mg for 3 to 4 weeks marked-ly increased the serum total and "indirect" reaction copper or caerulo-plasmin levels in 8 subjects with a variety of diseases. Values obtained after 4 weeks on 1 mg Estinyl were considerably higher than in any previously reported conditions.