Abstract
Erythrocytes of fetal sheep and goats show a diminution of mean volume, surface area and thickness, fetal hemoglobin, oxygen combining power, hemoglobin level and total number of corpuscles. The determinations approach the adult level after the seventh week, and reach this level after about a year. There is a relationship between the fetal hemoglobin, individual volume of the red cells, the surface area, as well as the affinity for oxygen of fetal hemoglobin, individual volume and the surface area. Alteration of thickness of red cells causes significant changes in exchange of gases.