Central Inhibitory Effects of Carbon Dioxide. III. Man

Abstract

18 patients were ventilated with various concns. of CO2-O2 for varying lengths of time and then were stimulated with super-threshold shocking current. Concns. of CO2 from 15-30% routinely prevented electrically induced seizures; with 30% CO2, 30 seconds of inhalation sufficed; with 15-20% mixtures, slightly longer periods of time were required.