CARDIAC EFFECTS OF ADRENALINE AND FELYPRESSIN AS VASOCONSTRICTORS IN LOCAL ANAESTHESIA FOR ORAL SURGERY UNDER DIAZEPAM SEDATION

Abstract

Brief precipitate heart rate rises of up to 40 beats/min were observed in nineteen of twenty-seven dental patients receiving local anaesthesia with 2 per cent lignocaine with adrenaline (1:80,000). No such rises were seen after 3 per cent prilocaine with felypressin (0.03 i.u./ml) which therefore may be preferable for patients with cardiovascular disease.