Prevention of Perinatal Transmission of Hepatitis B Virus Carrier State
- 1 December 1992
- journal article
- Published by Wiley in Pediatrics International
- Vol. 34 (6), 656-659
- https://doi.org/10.1111/j.1442-200x.1992.tb01026.x
Abstract
By means of passive and active immunization with hepatitis B immunoglobulin and hepatitis B vaccine, 396 of 407 babies born to hepatitis B antigen‐positive carrier mothers, were protected from establishing the hepatitis B virus (HBV) carrier state during a follow‐up period of 12 months or longer. Four infants developed the HBV carrier state before the completion of the immunoprophylaxis schedule, and another seven developed the state after the completion of the schedule. Seroconversion of anti‐HBc was observed in 26.8% of the successfully protected infants. In Japan a nationwide program to prevent the vertical transmission of HBV with these procedures was established in 1986, and so liver diseases due to HBV are expected to be eliminated in the near future.Keywords
This publication has 5 references indexed in Scilit:
- PREVENTION OF THE HBsAg CARRIER STATE IN NEWBORN INFANTS OF MOTHERS WHO ARE CHRONIC CARRIERS OF HBsAg AND HBeAg BY ADMINISTRATION OF HEPATITIS-B VACCINE AND HEPATITIS-B IMMUNOGLOBULINThe Lancet, 1984
- PREVENTION OF PERINATALLY TRANSMITTED HEPATITIS B VIRUS INFECTIONS WITH HEPATITIS B IMMUNE GLOBULIN AND HEPATITIS B VACCINEThe Lancet, 1983
- E Antigen and Anti-E in the Serum of Asymptomatic Carrier Mothers as Indicators of Positive and Negative Transmission of Hepatitis B Virus to Their InfantsNew England Journal of Medicine, 1976
- Vertical Transmission of Hepatitis B Antigen in TaiwanNew England Journal of Medicine, 1975
- Silent Maternal Transmission of Australia AntigenNature, 1974