Sulfhydryl Content of Normal Hemoglobin and Hemoglobin in in Sickle Cell Anemia.

Abstract
1. The titratable SH content of hemoglobin was determined amperometrically in saline, and found to approximate 2 moles SH per mole of normal hemoglobin and 3 moles SH per mole of hemoglobin from patients with sickle cell anemia. 2. The SH content of hemoglobin from two patients with sickle cell trait was greater than that of normal hemoglobin and less than that of sickle cell anemia hemoglobin suggesting that a mixture of the two types of hemoglobin was present in these patients.