MULTIPLE BIRTHS IN FORMER ORAL CONTRACEPTIVE USERS
- 1 July 1979
- journal article
- Published by Wiley in BJOG: An International Journal of Obstetrics and Gynaecology
- Vol. 86 (7), 557-562
- https://doi.org/10.1111/j.1471-0528.1979.tb10809.x
Abstract
Multiple births were studied in a cohort of 2953 former oral contraceptive users and 13,630 controls, all the women were interviewed post partum. There were 238 multiple births, a rate of 14.4/1000 deliveries. Former oral contraceptive users had 13.5/1000 sets of multiple births compared to 14.5/1000 in the controls. When women who had received treatment for anovulation were excluded, these rates were 11.1 and 12.7/1000 respectively, a difference which is not statistically significant. There was, however, a significant deficit of multiple births among the small group of former pill users who were underweight in relation to their height at the time of conception. Multiple births were also increased after stopping sequential pills and preparations containing high doses of oestrogen, and there was an excess of multiple births following breakthrough pregnancies. These findings, although statistically significant, are based on small numbers, and require confirmation from other studies.Keywords
This publication has 9 references indexed in Scilit:
- Fetal Loss, Twinning and Birth Weight after Oral-Contraceptive UseNew England Journal of Medicine, 1977
- Editorial: Worldwide decline in dizygotic twinning.BMJ, 1976
- Oral contraceptives and death from myocardial infarction.BMJ, 1975
- Oral Contraceptives and Congenital Limb-Reduction DefectsNew England Journal of Medicine, 1974
- Multiple PregnancyNew England Journal of Medicine, 1973
- Multiple Pregnancy Induced by Ovary HyperstimulationActa geneticae medicae et gemellologiae, 1972
- Secular changes in dizygotic twinning ratesJournal of Biosocial Science, 1972
- Pregnancy outcome following oral contraceptivesAmerican Journal of Obstetrics and Gynecology, 1971
- Large-Scale Study of an Oral ContraceptiveFertility and Sterility, 1968