The relationship between the serogroup antigen and lipopolysaccharide ofLegionella pneumophila
- 1 February 1986
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 96 (1), 39-48
- https://doi.org/10.1017/s0022172400062513
Abstract
SUMMARY: Serogroup-specific antigen was extracted from a number ofLegionella pneumophilastrains and compared with phenol-water extracted lipopolysaccharide on the basis of gel filtration, chemical analysis, SDS-PAGE and reaction with serogroup-specific antibody in immunoblots. Serogroup specificity is apparently borne by the O side-chains of the lipopolysaccharide, which, although smooth in type, partitions in the phenol phase. For four serogroup 1 strains tested, there was no qualitative correlation between O side-chain length and pulmonary virulence for guinea-pigs.This publication has 41 references indexed in Scilit:
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