Porphyrin Induction: Equivalent Effects of 5αH and 5βH Steroids in Chick Embryo Liver Cells
- 12 August 1977
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 197 (4304), 659-660
- https://doi.org/10.1126/science.877578
Abstract
The 5alphaH (A : B trans) and 5betaH (A : B cis) steroids are equipotent in inducing delta-aminolevulinic acid synthetase and porphyrin accumulation in chick embryo liver cells maintained in serum-free culture medium. Thus there is no specific steric requirement for porphyrin-inducing activity in steroids.This publication has 10 references indexed in Scilit:
- Cyproterone-Mediated Stimulation of δ-Aminolevulinic Acid Synthetase in Chick Embryo Liver CellsEndocrinology, 1976
- Drug-induced porphyrin biosynthesis—XV: Induction of porphyrin biosynthesis in chick embryo liver cells maintained in serum-free waymouth mediumBiochemical Pharmacology, 1976
- THYROID-HORMONE ENHANCEMENT OF DRUG-INDUCED PORPHYRIN BIOSYNTHESIS IN CHICK-EMBRYO LIVER-CELLS MAINTAINED IN SERUM-FREE WAYMOUTH MEDIUM1976
- STUDIES IN PORPHYRIAThe Journal of Experimental Medicine, 1972
- Drug-induced porphyrin biosynthesis—V: Effect of protohemin on the transcriptional and post-transcriptional phases of δ-aminolevulinic acid synthetase inductionBiochemical Pharmacology, 1972
- THE INFLUENCE OF SERUM ON UPTAKE, CONVERSION AND ACTION OF TESTOSTERONE IN RAT PROSTATE GLANDS IN ORGAN CULTUREJournal of Endocrinology, 1972
- Steroid Induction of Porphyrin Synthesis in Liver Cell CultureJournal of Biological Chemistry, 1967
- The Induction in Vitro of the Synthesis of δ-Aminolevulinic Acid Synthetase in Chemical Porphyria: A Response to Certain Drugs, Sex Hormones, and Foreign ChemicalsPublished by Elsevier ,1966
- INDUCTION IN VITRO OF SYNTHESIS OF DELTA-AMINOLEVULINIC ACID SYNTHETASE IN CHEMICAL PORPHYRIA - A RESPONSE TO CERTAIN DRUGS SEX HORMONES AND FOREIGN CHEMICALS1966