Chemical and Immunological Studies on a Heterophile Fraction Isolated from Bovine Erythrocyte Stroma
- 1 August 1953
- journal article
- research article
- Published by The American Association of Immunologists in The Journal of Immunology
- Vol. 71 (2), 45-51
- https://doi.org/10.4049/jimmunol.71.2.45
Abstract
Chemical analysis of an extract obtained from bovine erythrocyte stroma revealed it to be of a proteinaceous nature. Nine amino acids were identified as lysine, glutamic acid, serine, glycine, threonine, alanine, aspartic acid, leucine and isoleucine from acid hydrolysates of the extract via paper chromatography. Electrophoretic determinations indicated the extract to contain four discernible portions, three of which carried a portion of the immunologic activity. Enzymatic hydrolysis of the extract with proteinases destroyed all immunologic activity.Keywords
This publication has 4 references indexed in Scilit:
- Heterophile Antibodies of Infectious MononucleosisAmerican Journal of Clinical Pathology, 1952
- Beef Erythrocyte Extracts Reacting with Hemagglutinins in Infectious Mononucleosis and in Horse Serum SicknessExperimental Biology and Medicine, 1949
- Nature of the Heterogenetic Hapten Reacting with Hemagglutinins in Horse Serum SicknessExperimental Biology and Medicine, 1948
- The Relations Between Certain Heterophile Antibodies and AntigensThe Journal of Infectious Diseases, 1936