Prodigiosin. I. Antibiotic Action on Coccidioides immitis in Vitro.

Abstract

Prodigiosin, the red pigment of Serratia marcescens. was fungistatic for C. immitis in dilutions through 1:500,000. It was fungicidal after 48 hrs. of exposure in dilutions through 1:100,000. Prodigiosin HC1, perchlorate and a water-soluble glutamic acid derivative demonstrated similar in vitro effectiveness.