Medroxyprogesterone induced Cushing's syndrome
- 1 December 1990
- journal article
- case report
- Published by Wiley in Australian and New Zealand Journal of Medicine
- Vol. 20 (6), 824-825
- https://doi.org/10.1111/j.1445-5994.1990.tb00433.x
Abstract
A 74-year old female taking medroxyprogesterone acetate (MPA) presented with Cushing's syndrome together with low serum cortisol and plasma ACTH and an impaired response to synthetic ACTH (Synacthen, CIBA). When the medroxyprogesterone therapy was ceased the cushingoid features resolved and serum cortisol, ACTH and ACTH responsiveness all returned to normal. The MPA was acting as an exogenous glucocorticoid causing Cushing's syndrome.Keywords
This publication has 6 references indexed in Scilit:
- The Cushing Syndrome Induced by Medroxyprogesterone AcetateAnnals of Internal Medicine, 1989
- The Effect of Medroxyprogesterone Acetate on the Pituitary-Adrenal AxisJournal of Clinical Endocrinology & Metabolism, 1976
- Adverse effects of large doses ofmedroxyprogesterone (MPA) in idiopathic isosexual precocityThe Journal of Pediatrics, 1971
- Natural History of Pituitary-Adrenal Recovery Following Long-Term Suppression with Corticosteroids1Journal of Clinical Endocrinology & Metabolism, 1965
- THE CORTISONE-LIKE EFFECT OF 6α=METHYL-17α-ACETOXYPROGESTERONE IN THE ADRENALECTOMIZED MANActa Endocrinologica, 1963