The effect of insulin on Fru‐2,6‐P2 levels in human fibroblasts
- 4 June 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 171 (1), 117-120
- https://doi.org/10.1016/0014-5793(84)80470-6
Abstract
We report that fructose 2,6-bisphosphate (Fru-2,6-P2) levels in quiescent human fibroblasts stimulated with insulin treatment increase in a time- and dose-dependent manner. The biochemical role of the sugar phosphate in the cellular response to the hormone which controls carbohydrate metabolism and acts as mitogenic factor is discussed.Keywords
This publication has 14 references indexed in Scilit:
- Fructose 2,6‐bisphosphate in relation with the resumption of metabolic activity in slices of Jerusalem artichoke tubersFEBS Letters, 1983
- Short‐term regulation of glycolysis by insulin and dexamethasone in cultured rat hepatocytesEuropean Journal of Biochemistry, 1983
- Increase of the glycolytic rate in human resting fibroblasts following serum stimulationFEBS Letters, 1983
- A Kinetic Study of Pyrophosphate: Fructose‐6‐Phosphate Phosphotransferase from Potato TubersEuropean Journal of Biochemistry, 1982
- The effect of insulin and glucose on fructose-2,6-P2 in hepatocytesBiochemical and Biophysical Research Communications, 1982
- Growth Factors in Mammalian Cell CultureAnnual Review of Biochemistry, 1976
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- Control of growth of mammalian cells in cell cultureNature, 1975
- DNA Synthesis in Human Fibroblasts: Stimulation by Insulin and by Nonsuppressible Insulin-like Activity (NSILA-S)Journal of Clinical Endocrinology & Metabolism, 1974
- Fibroblasts as an Experimental Tool in Metabolic and Hormone StudiesEuropean Journal of Clinical Investigation, 1973