Binuclear ruthenium(II) phenanthroline compounds with extreme binding affinity for DNA
- 1 January 1996
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 18,p. 2145-2146
- https://doi.org/10.1039/cc9960002145
Abstract
Dimeric homochiral ruthenium complexes [L2Ru{dppz(11-11′)ddpz}RuL2]4+(L = 1,10-phenanthroline, 2,2′-bipyridyl; dppz = dipyrido[3,2-A: 2′,3′-C]phenazine) bind extremely strongly to duplex DNA with different binding geometries for the ΔΔ and ΔΔ enantiomers of the phenanthroline complex but with similar geometries for the bipyridyl complex enantiomers.Keywords
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