Olfactory uptake of manganese requires DMT1 and is enhanced by anemia
Open Access
- 20 November 2006
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 21 (1), 223-230
- https://doi.org/10.1096/fj.06-6710com
Abstract
Manganese, an essential nutrient, can also elicit toxicity in the central nervous system (CNS). The route of exposure strongly influences the potential neurotoxicity of manganese‐containing compounds...Keywords
Funding Information
- National Institutes of Health (DK60528/ES014638)
- American Welding Society
- National Institute of Environmental Health Sciences (P01 ES012874)
- U.S. Environmental Protection Agency
This publication has 65 references indexed in Scilit:
- Water Manganese Exposure and Children’s Intellectual Function in Araihazar, BangladeshEnvironmental Health Perspectives, 2006
- Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste siteNeuroToxicology, 2005
- IRONSTATUS ANDNEURALFUNCTIONINGAnnual Review of Nutrition, 2003
- Odorant receptor expression as a function of neuronal maturity in the adult rodent olfactory systemJournal of Comparative Neurology, 2003
- Direct Olfactory Transport of Inhaled Manganese (54MnCl2) to the Rat Brain: Toxicokinetic Investigations in a Unilateral Nasal Occlusion ModelToxicology and Applied Pharmacology, 2000
- The Human Nramp2 Gene: Characterization of the Gene Structure, Alternative Splicing, Promoter Region and PolymorphismsBlood Cells, Molecules, and Diseases, 1998
- Computer Simulation of Inspiratory Airflow in All Regions of the F344 Rat Nasal PassagesToxicology and Applied Pharmacology, 1997
- Manganese and Copper-Zinc Superoxide Dismutases in the Human Olfactory Mucosa: Increased Immunoreactivity in Alzheimer's DiseaseExperimental Neurology, 1996
- An immunochemical, ultrastructural, and developmental characterization of the horizontal basal cells of rat olfactory epitheliumJournal of Comparative Neurology, 1995
- Possible Health Effects of High Manganese Concentration in Drinking WaterArchives of environmental health, 1989