Neurologic Disorders in Renal Failure

Abstract

Uremic NeuropathyNeuropathy occurs in at least 65 per cent of patients who are about to begin dialysis for chronic renal failure,⁷⁰ and is perhaps the most common neurologic consequence of chronic uremia. It was described by Asbury and his colleagues⁷¹ as a distal, symmetrical, mixed, sensorimotor polyneuropathy, affecting the lower limbs to a greater extent than the upper limbs. It is clinically indistinguishable from the neuropathies associated with chronic alcohol abuse, diabetes mellitus, and lupus erythematosus, to name but a few. The rate of progression, severity, prominence of motor or sensory signs, and prevalence of dysesthesia are quite variable. . . .