γδ T cells mitigate the organ injury and mortality of sepsis
Open Access
- 6 December 2007
- journal article
- pathogenesis and-host-defense
- Published by Oxford University Press (OUP) in Journal of Leukocyte Biology
- Vol. 83 (3), 581-588
- https://doi.org/10.1189/jlb.0707507
Abstract
Journal of Leukocyte Biology considers manuscripts of original investigations focusing on the origins, developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes, and other cells involved in host defense. These include full-length papers on original research, rapid communications of new discoveries, letters, commentaries, and invited reviews.Keywords
Funding Information
- National Institutes of Health (R01 GM72760)
- Shriner’s of North American Project (#8560)
This publication has 33 references indexed in Scilit:
- THERMAL INJURY ELEVATES THE INFLAMMATORY MONOCYTE SUBPOPULATION IN MULTIPLE COMPARTMENTSShock, 2007
- MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsisThe Journal of Experimental Medicine, 2007
- Deficiency of γδ T lymphocytes contributes to mortality and immunosuppression in sepsisAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2006
- Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levelsAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2005
- DIMINISHED BACTERIAL CLEARANCE IS ASSOCIATED WITH DECREASED IL-12 AND INTERFERON-?? PRODUCTION BUT A SUSTAINED PROINFLAMMATORY RESPONSE IN A MURINE MODEL OF POSTSEPTIC IMMUNOSUPPRESSIONShock, 2004
- Phagocytosis by neutrophilsMicrobes and Infection, 2003
- Immunoregulation in the tissues by γδ T cellsNature Reviews Immunology, 2003
- Signaling from cytokine receptors that affect TH1 responsesFrontiers in Bioscience-Landmark, 2002
- Exaggerated Proinflammatory and Th1 Responses in the Absence of γ/δ T Cells after Infection withListeria monocytogenesInfection and Immunity, 2001
- Patterns of lymphokine secretion amongst mouse γδ T cell clonesEuropean Journal of Immunology, 1997