Fragile sites in human chromosomes I The effect of methionine on the Xq fragile site
- 23 April 1981
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 19 (4), 228-232
- https://doi.org/10.1111/j.1399-0004.1981.tb00703.x
Abstract
The Xq fragile site found in males having non-specific X-linked mental retardation was studied by varying the chemical and physical parameters of leukocyte cultures. Methionine was required for marker expression in both medium 199 and MEM [minimal essential medium]. Banding studies indicated that methionine does not function as a stabilizing factor for the fragile site on Xq.Keywords
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